Archives of Clinical Microbiology

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A Relationship between Sleep Cycle and Immunity against COVID-19 Infection

Writtik Maity, Subhasish Maity, Sidhant Nandi, Satayu Devi

The outbreak of coronavirus in 2019 has devastated the world and led to a global pandemic. The infectious disease COVID-19 which is caused by severe acute respiratory syndrome coronavirus-2 (SARS CoV-2) emerged from a zoonotic reservoir. The data suggest that the recent outbreak has similar genetic emergence to those of SARS and MERS. The patients are assisted with major breathing problems and the rapid transmission results in the apocalypse for humans. To arrest the viral infection, immunity is the preliminary key of the individual for defending against the pathogen. The production of T cells plays a crucial role in the immune system response to the virus. Therefore, sleep and the circadian system strives for an impact on immune functions. It has further reinforced the major and specific role of sleep that takes part in boosting the immune system. In this review, we provide an emphasis on pathogenicity, adaptive immunity in the terms of enhancing the system and also the role of the sleep cycle in context to the COVID-19 infection.