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Journal of Neurology and Neuroscience

  • ISSN: 2171-6625
  • Journal h-index: 18
  • Journal CiteScore: 4.35
  • Journal Impact Factor: 3.75
  • Average acceptance to publication time (5-7 days)
  • Average article processing time (30-45 days) Less than 5 volumes 30 days
    8 - 9 volumes 40 days
    10 and more volumes 45 days
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Abstract

Alzheimer's Disease and Diabetes: Diffusion Tensor Imaging as a Probable Diagnostic Measure

Arshia Zarduei, Bahar Pourmennati and Asma Darvishi

The main neuropathological features of Alzheimer’s disease, a chronic neurodegenerative condition, are amyloid plaques (extracellular lesions) and neurofibrillary tangles (intercellular lesions) agglomeration in brain tissue. Some studies illustrate that Diabetes Mellitus type II might facilitate accumulation of amyloid-beta in brain tissue; can dispose patients to Alzheimer’s disease. In brain, water molecules mainly diffuse in the same directions as the neural pathways; amyloid-beta depositions as obstacles alter the normal directions of water motion in brain tissue ergo presenting as abnormalities in images taken by Diffusion Tensor Imaging that can be utilized for early diagnosis of Alzheimer’s disease.