International Journal of Drug Development and Research

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Anti Bacterial and Anti Inflammatory efficacy of Zingiber officinale and Decalepis hamiltonii ? In Vitro Study

Arun kumar M, Tejaswi B, Susila V Anand

Aim: To evaluate the in vitro anti bacterial and anti inflammatory potential of Zingiber Officinale and Decalepis Hamiltonii against E. faecalis. Materials and Methods: Ethanolic extract of Zingiber and Decalepis was subjected to microbiological assay to determine its Maximum zone of inhibition using Agar disk diffusion test, minimum inhibitory concentration using serial broth dilution method and anti inflammatory potential using protein denaturation assay against E. faecalis. Results: Ethanolic extract of Zingiber and Decalepis showed: (a) Maximum zone of inhibition of 20 mm and 24 mm respectively, (b) MIC of 5% and 2.5%respectively, (C) Protein denaturation assay value (IC50) of 115 and 80 respectively. Conclusion: Ethanolic extract of Zingiber and Decalepis was found to possess both anti bacterial and anti-inflammatory potential against E. faecalis.