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International Journal of Drug Development and Research

  • ISSN: 0975-9344
  • Journal h-index: 49
  • Journal CiteScore: 11.20
  • Journal Impact Factor: 8.24
  • Average acceptance to publication time (5-7 days)
  • Average article processing time (30-45 days) Less than 5 volumes 30 days
    8 - 9 volumes 40 days
    10 and more volumes 45 days
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Abstract

Antioxidant activity and Phytochemical Analysis of Datura metel

Sundaramoorthy Sangeetha, Mani Deepa, Nagaraj Sugitha, Sathiavelu Mythili, Arunachalam Sathiavelu

The objective of this study is to determine antioxidant activity and phytochemical analysis of Datura metel by using four different types of solvents n- hexane, ethyl acetate, chloroform, and methanol. Sequencing extract was prepared. The antioxidant activity of different solvent extracts from the leaves of Datura metel was tested by Total phenolic content, DPPH scavenging activity, Hydroxyl radical scavenging activity, Reducing power assay, and  –carotene bleaching activity. The antioxidant activity was performed at four different concentrations ranging from 25- 100mg/ml.The phytochemical analysis of all crude extracts showed a positive result for alkaloids, saponins, flavonoids, tannins, glycosides, aminoacids and phlobatannins, whereas steroids and terpenoids are absent. Chloroform extract exhibited highest antioxidant activity with increase in concentration.