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International Journal of Drug Development and Research

  • ISSN: 0975-9344
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Abstract

Bacterial isolates from lonar lake produce antimicrobial factors effective against MDR pathogen

Anushka Salvi, A Harsulkar

Lonar lake being one of its kind is a crater impact saline lake that harbors extremophile vegetation and organisms with unusual properties. Several microorganisms have been isolated from this lake and studied for their properties. The current project involved an antimicrobial lonar isolate: Bacillus sp. which was screened for its activity against six multi-drug resistant human pathogens and showed positive results against Enterococcus faecalis. The growth parameters of the antibacterial Bacillus sp. were optimized and the compound was extracted using chloroform as solvent. The crude extract and partially purified compound was further characterized using TLC and HRMS.

Published Date: 2023-09-22; Received Date: 2019-09-03