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Breast Cancer Progression and Current Therapeutic Approach

Aradhana Singh and Anupam Basu

Breast cancer is the most common malignancy and a leading cause of deaths of women around the globe. Tumor originated from the mammary gland are the most recurrently diagnosed malignancies worldwide and register around 14% of all deaths, making breast cancer the most fatal neoplasm in women. Breast cancer can starts as a local disease however it can metastasize to distant part of body particularly to lymph node, bone and spine which makes it deadliest. Breast cancer can be categorized into a number of types on the basis of size, possession of specific marker, grades of metastasis etc. Genetic predisposition marks an important place in list of risk factors associated with breast cancer but the sporadic forms are remarkable. Breast cancer is curable if diagnosed at very early stage although there are several therapies like chemotherapy, hormonal therapy, radiation therapy, and targeted therapy etc. which improve expectancy and quality of life in later stages also.