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International Journal of Drug Development and Research

  • ISSN: 0975-9344
  • Journal h-index: 49
  • Journal CiteScore: 11.20
  • Journal Impact Factor: 8.24
  • Average acceptance to publication time (5-7 days)
  • Average article processing time (30-45 days) Less than 5 volumes 30 days
    8 - 9 volumes 40 days
    10 and more volumes 45 days
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Abstract

Carbamazepine Induced Hypertension: A Case Report

Zylfije Hundozi, Nazmije Ibishi, Fisnik Jashari and Nebih Musliu

We report a case of 70 year old women with primary hypertension and trigeminal neuralgia of the right side of face. Hypertension was well controlled with one antihypertensive drug for long time which became uncontrolled after administrating Carbamazepine for trigeminal neuralgia. The adverse effects of carbamazepine include cardiac conduction abnormalities, aplastic anemia, bone marrow depression, congestive heart failure, peripheral edema. Hypertension has rarely been documented with therapeutic doses of carbamazepine. On admission the patient had blood pressure 180/110 mmHg, despite an antihypertensive therapy. Treatment with additional antihypertensive medication did not reduce her blood pressure. After discontinuation of Carbamazepine levels of blood pressure were normal. Therefore, we considered that resistant hypertension was induced by oral carbamazepine therapy.