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Archives of Clinical Microbiology

  • ISSN: 1989-8436
  • Journal h-index: 24
  • Journal CiteScore: 8.01
  • Journal Impact Factor: 7.55
  • Average acceptance to publication time (5-7 days)
  • Average article processing time (30-45 days) Less than 5 volumes 30 days
    8 - 9 volumes 40 days
    10 and more volumes 45 days
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Abstract

Cloning and expression of bacteriocins of Pediococcus spp.: A review

Balvir Kumar, Praveen P. Balgir, Baljinder Kaur, Neena Garg

Natural food biopreservatives have always’s remained the preference of health consciousconsumers. This necessity has led to the studies exploring better alternativeswhich are more acceptable, economical and safer than chemical preservatives. Bacteriocinsare one of such compounds produced by lactic acid bacteria which offera great potential to contribute in food, health and pharmaceutical industry. Presentreview focuses the complete biochemical, functional and molecular genetic characterizationof bacteriocins produced by Pediococcus spp. A great deal of diverseheterologous expression systems have been exploited for cloning, expression andpurification of pediocins at laboratory scale but data is lacking for industrial processes.Thus, there is an urgent need to design low cost, industrially viable and continuoussystem in order to exploit these natural bioactive compounds in food andpharmaceutical industry