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Translational Biomedicine

  • ISSN: 2172-0479
  • Journal h-index: 12
  • Journal CiteScore: 8.06
  • Journal Impact Factor: 1.0
  • Average acceptance to publication time (5-7 days)
  • Average article processing time (30-45 days) Less than 5 volumes 30 days
    8 - 9 volumes 40 days
    10 and more volumes 45 days
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Abstract

Current Scenario of Covid-19 in Translational Medicine

Gregory John Hollis*

The COVID-19 epidemic caused by the SARS-CoV-2 virus has reached pandemic proportions and caused worldwide instability. With limited ICU beds and insufficient respiratory support, healthcare systems were unprepared to treat patients who progressed to a severe acute respiratory syndrome, the dire sort of the COVID-19 disease. Current antiviral candidates tested or approved for COVID-19 are compounds that are repositioned from other indications. Generally, drugs are often repositioned for the treatment of the SARSCoV-2 infection if they need evidence of in vitro inhibition against human coronaviruses (CoV). For instance , remdesivir, which was originally intended for treating Ebola, has been recently approved for the treatment of COVID-19 requiring hospitalization; the anti-malaria drug chloroquine is additionally being evaluated for COVID-19 treatment; the anti-HIV drug combination lopinavir-ritonavir is employed off-label in many lower-income countries against COVID-19. Antivirals, however, may come short in severely ill COVID-19 patients. The ?novel? coronavirus disease 2019 (abbreviated ?COVID-19?) is that the third coronavirus outbreak emerging during the past 20 years . This communicable disease , sustained by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), has been recently declared a worldwide pandemic by the planet Health Organization.