International Journal of Drug Development and Research

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Design and Evaluation of Artocarpus heterophyllus Incorporated Herbal Effervescent Granules

Yash Shah*, Chiragi Patel, Tanvi Kachhiya, Subhashchandra Patel and DR. Tejal Gandhi

The jackfruit, or Artocarpus heterophyllus Lam., is a tropical climacteric fruit that is a member of the Moraceae family. The jackfruit is full of nutrients; some of the phytochemicals are proanthocyanidin, flavonoids, and artemisinin. The jack fruits, leaves, and bark, have been extensively utilized in traditional medicine because of their anticarcinogenic, antiinflammatory, and hypoglycemic benefits. The present study was undertaken to formulate and evaluate the effervescent granules content of Artocarpus heterophyllus extract. Three batches of effervescent granules were prepared from which batch II was found to give good flow properties. The phytochemicals found in jackfruit extract were proanthocyanidin, flavonoids, polyphenols, and the creation of a new solvent system for thin-layer chromatography of methanolic (jackfruit) extract. Methanolic extract of jackfruit shows an Rf value of 0.38 by using a 70:30 ratio of Acetone to n-hexane. FTIR and UV spectroscopy and several post-formulation tests were used to identify the primary ingredient present in both extract and effervescent granules. The results revealed that the extract has the highest concentration of proanthocyanidin, flavonoids, and phenolic components, and the λmax was found to be at 278nm. Moreover, FTIR studies revealed that the extract from Artocarpus heterophyllous has no chemical interactions with the other substances.


Artocarpus heterophyllus; Effervescent granules; Citric: tartaric: sodium bicarbonate (1:2:4); Methanolic extract

Published Date: 2023-05-29; Received Date: 2023-05-01