SOLANKI SAGAR D, DR. PATEL PARESH U, DR.SUHAGIYA BHANUBHAI N
A simple liquid chromatographic method was developed and validated for determination of sumatriptan succinate (SUMA) in tablet dosage form. The analysis is performed at ambient temperature on a reversed-phase C18 column with detection at 232 nm. The mobile phase consisting of ACN : Water (18:82) and 0.05% v/v trifluro acetic acid was added in water at a constant flow rate of 1.0 ml/min. The method was validated for accuracy, precision, linearity and specificity. The linearity was found to be in the range of 10-50 ppm. The % recovery was found between the range of 98.0% to 102.0% of the labeled value. The proposed method was successfully applied for the routine quantitative analysis of tablets containing SUMA
