Archives in Cancer Research

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Disparity in Metabolic Conditions among Hispanic/Latina Women with Breast Cancer

Joh D, Botrus G, Dwivedi AK, Dongur L and Nahleh Z*

Background: Breast cancer is the most common cancer in Hispanic/Latina women. Common metabolic conditions prevalent in American Hispanics include diabetes mellitus, dyslipidemia, hypertension, and obesity and have been associated with poor overall survival. The association of such coexisting conditions with breast cancer risk, treatment and breast cancer characteristics in this population is largely understudied. In this study, we sought to explore the prevalence of one or combination of these comorbid conditions with breast cancer and possible association with breast cancer characteristics and subtypes in a predominantly Hispanic patient population.

Methods: After IRB approval, we conducted a retrospective cross-sectional study of consecutive breast cancer patients treated in a University based tertiary medical center in the large border city of El Paso, TX. We evaluated the prevalence of 4 common metabolic conditions in a Hispanic patient population using the breast cancer center database of patients treated between 2005 and 2014. Adjusted association analyses were carried out using multiple Poisson regression analyses and results were presented with prevalence ratio (PR) and p-value.