Journal of Neurology and Neuroscience

  • ISSN: 2171-6625
  • Journal h-index: 18
  • Journal CiteScore: 4.35
  • Journal Impact Factor: 3.75
  • Average acceptance to publication time (5-7 days)
  • Average article processing time (30-45 days) Less than 5 volumes 30 days
    8 - 9 volumes 40 days
    10 and more volumes 45 days
Awards Nomination 20+ Million Readerbase
Indexed In
  • Open J Gate
  • Genamics JournalSeek
  • The Global Impact Factor (GIF)
  • China National Knowledge Infrastructure (CNKI)
  • Directory of Research Journal Indexing (DRJI)
  • OCLC- WorldCat
  • Proquest Summons
  • Scientific Journal Impact Factor (SJIF)
  • Euro Pub
  • Google Scholar
  • Secret Search Engine Labs
Share This Page


Effectiveness of Endoscopic Endonasal Transsphenoidal Surgery Using a Neuronavigation: Clinical Results of 178 Pituitary Adenomas

Manabu Shirakawa, Shinichi Yoshimura, Kiyofumi Yamada, Tomoko Iida, Kazutaka Uchida, Yoshihiro Takada and Reiichi Ishikura

Title: Effectiveness of endoscopic endonasal transsphenoidal surgery using a neuronavigation: Clinical results of 178 pituitary adenomas

Background: The present study assesses endoscopic endonasal transsphenoidal surgery using neuronavigation for pituitary adenoma.

Methods and findings: Data were analyzed from 178 consecutive patients with pituitary adenomas who underwent endoscopic endonasal transsphenoidal surgery using neuronavigation between April 2007 and May 2014. Rates of gross total removal and overall hormone remission in patients with microadenomas were 64% (114/178) and 90.9% (30/32), respectively. However, the rate of hormonal remission was lower for macroadenomas that produce growth hormone 64.3% (9/14). The rate of complications was 2.1% (4/178) including two patients with anterior pituitary insufficiency and one each with vision deterioration and permanent diabetes insipidus.

Conclusion: Rates of complete removal and hormone remission were higher and complication rates were lower after endoscopic endonasal transsphenoidal surgery using neuronavigation to treat pituitary adenoma.