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Efficacy of Combined Neo-Adjuvant Chemotherapy and Radical Resection for a Giant Chondrosarcoma of the Gluteal Region

Binyom PR, Daniel Handy Eone, Omboto S, Akem Dimala C, Abolo Mbenti and Ngo Nonga Bernadette

Chondrosarcoma is a malignant tumor of cartilaginous origin, which could have a smooth or rough surface and a firm or elastic consistency. It is predominantly found in young adults. Depending on their histologic grading and forms, these tumors characteristically metastasized first to the lungs. One of the most common clinical characteristic is the rapid growth of the tumor, rending its therapeutic approach complex: surgery and adjuvant radiotherapy, surgery and adjuvant chemo-radiation. High failure rate have been reported in the literature about the results of these combined therapies, with the impression that chondrosarcoma is resistant to chemotherapy and radiotherapy. There is very few reported cases of chondrosarcoma in Africa and, no study about the sensitivity of the tumor to multiple drugs chemotherapy have been reported from Cameroon. We are reporting herein the case of a giant grade II, chondrosarcoma of the left coxofemoral and gluteal region which has been successfully managed by neoadjuvant chemotherapy associated with external application and massage by a camphor based essential oil followed by a radical resection of the residual tumor.