Numerous issues arise in the field of solubility augmentation. Pharmacosomes, a revolutionary method based on lipid medication delivery, have emerged. Pharmacosomes are covalently bound, colloidal, nanometric-size micelles, vesicles, or hexagonal assemblies of colloidal drug dispersions to the phospholipid. Due to their special qualities such tiny size, amphiphilicity, active drug loading, high entrapment efficiency, and stability, they serve as suitable carriers for drug administration fairly accurately. In addition to lowering therapy costs, drug leakage and toxicity, increasing the bioavailability of poorly soluble medications, and having restorative benefits, they aid in the regulated release of drugs at the site of action. Ayurveda's innovative methods for discovering active ingredients have significantly aided in the discovery of new drugs. A fundamental change in the practise of medicine has been brought about by recent improvements in the bioavailability enhancement of pharmaceuticals by substances of herbal origin. As a outcome, a bibliographic study was conducted by examining traditional textbooks and peer-reviewed articles, accessing internationally renowned scientific databases from the previous 30 years. It has been demonstrated that herbal bioenhancers can improve the bioavailability and bioefficacy of a variety of therapeutic classes, including antibiotics, antituberculosis, antiviral, antifungal, and anticancer medicines, at modest doses. The oral absorption of nutraceuticals such vitamins, minerals, amino acids, and certain herbal components has also been improved. Their primary modes of action involve drug metabolism, drug absorption, and drug target interaction.
Published Date: 2022-08-29; Received Date: 2022-07-29
