International Journal of Drug Development and Research

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In Vitro Evaluation of Antibacterial Activity of Ethanolic and Aqueous leaf Extracts of Sesbania Grandiflora (Linn) Against Clinical Pathogens


The aim of the present study is to evaluate the antibacterial activity of ethanolic and aqueous leaf extract of Sesbania grandiflora Linn on selected bacterial species. Sesbania grandiflora (Linn) is a medicinal herb belongs to the family Leguminosae .The various parts of the plant like roots, bark, leaves, flower and fruit are known to possess different pharmacological properties. The leaf extract of Sesbania possess good anticonvulsant and anxiolytic activity. The leaves of Sesbania is also found to possess hepatoprotective and potent anti oxidant and anti urolithiatic activity .The Ethanolic and Aqueous extract of leaves were screened for the antimicrobial activity by agar well diffusion method. The test organisms used were Staphylococcus aureus, E.coli, Klebsiella pneumoniae, Psuedomonas aeruginosa and Bacillus subtilus. The results obtained from the study showed that the ethanolic extract has significant antibacterial activity on Staphylococcus aureus and E.coli compared with standards