International Journal of Drug Development and Research

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Investigations on important secondary metabolites in Dolichandrone falcata Seem. Leaves Using GC-MS

Ekade P. P., Manik S. R.*

Objective: To find out important secondary metabolites that gives much medicinal importance to Dolichandrone falcata in traditional tribal practices. Methods: The preliminary phytochemical screening is performed using the methods of Harborne and Raman. The preliminary screening reveals the presence of steroids, flavonoids, tannins and saponins. Gas Chromatography – Mass Spectroscopy analysis of Dolichandrone falcata leaves is performed on three extracts namely methanol, chloroform and dichloromethane solvents. Results: The methanol extract analysis shows the presence of many biologically important compounds like phytol, octadeconoic acid etc. The chloroform extract exhibit the presence of vitamin E, n-hexadecanoic acid etc. While dichloromethane extract analysis shows the highest amount of vitamin E and its derivatives. Conclusion: The compounds responsible for antimicrobial, anti inflammatory and anti-oxidant activity were found in the present analysis. Apart from this the leaves of Dolichandrone falcata is a good source of vitamin E and its derivatives.