International Journal of Drug Development and Research

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Mycobacterium Oral Immunogenicity Tuberculosis Infection

Tahar K*

Orientation and considerations, the long-term success of kidney transplant recipients is hampered by post-transplant tuberculosis (TB). In order to demonstrate the pattern, risk factors, and prognosis of TB infection in our transplant patients, it was important for us to provide specific examples. Patients and techniques this study involved a retrospective analysis of the medical records of 491 people who received kidney transplants at our hospital between January 1986 and December 2009. The demographic information, transplant characteristics, clinical symptoms, diagnostic standards, treatment approach, and long-term prognosis of this patient cohort were examined. 16 patients (32%), with a mean age of 32,5 12,7 (range: 13-60) years and a mean post-transplant time of 36,6 months, acquired post-transplant TB (range: 12,3 months–15,9 years). 10/16 (62,6%) of the illnesses had pulmonary manifestations. The ESAT6 and CFP10 lines of transgenic carrot plants have been developed to produce Mycobacterium tuberculosis proteins. For ESAT6 and CFP10, the target proteins are present in carrot storage roots at concentrations that are not less than 0.056% and 0.002% of the total storage protein (TSP), respectively. Oral vaccination of mice outcome in the induction of both humoral and cell-mediated immunity, as has been demonstrated. These outcomes indicate that the proteins under consideration are suitable as a potential edible tuberculosis vaccine.

Published Date: 2022-08-29; Received Date: 2022-07-29