Translational Biomedicine

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Nonsyndromic Phocomelia: A Case Series

Anurag Sharma, Rajesh Chaudhary, Ankit Shukla, Usha K Chaudhary, Kulbhushan Sharma and Atul Gupta

Phocomelia is a rare congenital disorder seen in new borns. It means ‘seal limbs’ derived from greek language. The incidence of this disorder is very low, and true phocomelia cases are further low, hence there are not many studies on this disorder. Thalidomide was responsible for bringing this drug into limelight. In this report we have described two cases of isolated nonsyndromic phocomelia where there was no history to drug or radiation exposure during intra-uterine period thus showing that there are factors other than thalidomide, which needs to be studied.