Archives of Medicine

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Osteoporosis associated with Pregnancy

Srinivas Pentyala, Aleef Rahman, Pooja Mysore, Thomas Tumillo, Avijit Roy, Sahana Pentyala, John Muller, Krupali Chokshi, Sardar Khan

Osteoporosis has been recognized as one of the major diseases affecting individuals globally, including pregnant women and women who lactate. An enormous amount of calcium and other minerals are required for nourishment during pregnancy and lactation. During these critical stages, the homeostasis between osteoblasts and osteoclasts is perturbed. A higher serum level of calcium and minerals are needed due to a decrease in Bone Mass Density (BMD). Due to the decrease in bone mass, these people have a greater chance of acquiring osteoporosis and correspondingly any osteoporosis-related fractures. This review focuses on the physiology of bone and the development of osteoporosis during pregnancy and lactation.