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Annals of Clinical and Laboratory Research

  • ISSN: 2386-5180
  • Journal h-index: 19
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Abstract

Outcome of Antenatal Hydronephrosis

Seçil Conkar, Vüset Memmedov and Sevgi Mir

Objective: The aim of this study was to report the outcome of infants with antenatal hydronephrosis.

Methods: All patients diagnosed with isolated fetal renal pelvic dilatation (RPD) were prospectively followed between January 2009 and December 2010. The events of interest were the presence of uropathy, requiring surgical intervention, RPD resolution and urinary tract infection (UTI). The diagnosis was established by ultrasound in 49 neonates with antenatal hydronephrosis (ANH) and they were submitted to a specific post-natal evaluative protocol with a follow-up period of 2 years. RPD was classified as mild (5-9.9 mm), moderate (10-14.9 mm) or severe (≥15 mm).

Results: A total of 49 patients were included in the analysis; 32 were allocated to the group of non- significant findings (65.3%) and 17 to the group of significant uropathy (34.6%). It was detected that 8 (16.3%) of the group of significant uropathy had ureteropelvic junction obstruction (UPJO), 3 (6.1%) had vesicoureteral reflux (VUR), and 3 (6.1%) had posterior urethral valves (PUV). 9 patients (18.3%) required surgical intervention because of obstructive uropathy. Of the 49 infants with RPD, 20 (40.8%) presented UTI and 32 (65.3%) presented RPD resolution during followup. In our prospective study, it was shown that 81.9% of infants with moderate RPD had UTI during follow-up.

Conclusion: Our findings suggested that, in contrast to patients with mild/severe RPD, infants with moderate RPD required a strict clinical surveillance for UTI.