Annals of Clinical and Laboratory Research

  • Journal h-index: 14
  • Journal CiteScore: 2.64
  • Journal Impact Factor: 1.89
  • Average acceptance to publication time (5-7 days)
  • Average article processing time (30-45 days) Less than 5 volumes 30 days
    8 - 9 volumes 40 days
    10 and more volumes 45 days
Indexed In
  • Genamics JournalSeek
  • China National Knowledge Infrastructure (CNKI)
  • CiteFactor
  • Directory of Research Journal Indexing (DRJI)
  • Publons
  • Euro Pub
  • Google Scholar
  • Secret Search Engine Labs
Share This Page


Pertinence of the Immunofixation Prescription in Heterogeneity Restrictions of the Gammaglobulin Zone

Soufiane Nader*, Adam Bentahila, Mehdi Ztoute, Abdelhamid Zrara and Amina Benouda

Monoclonal gammopathies are regularly materialized on an EPP by a narrow peak in the gamma zone. Sometimes this expression is expressed by a deformation which affects the Gaussian aspect of the curve expressing these gamma globulins it is called restriction of the heterogeneity of the gamma globulins, this can mask a monoclonal gammopathy. Our objective is to study the relevance of prescribing immunofixation in this circumstance. This is a retrospective study of all serum protein electrophoresis completed by immunofixation. 16 patients had restriction of gammaglobulin heterogeneity. Immunofixation revealed that 12 cases (75%) out of 16 had indeed monoclonal gammopathy. It can thus be concluded that the restrictions of gamma heterogeneity in elderly patients should raise the suspicion of monoclonal gammopathies.

Received Date: 2022-04-27