Raj Soni, Dilip Gadhavi
Background: Polycystic ovary syndrome (PCOS) is a common endocrine system disorder among women of reproductive age. Women with PCOS may have enlarged ovaries that contain small collections of fluid (Follicles). Alternative therapy including natural minerals has been emerging in addition to established medical and surgical treatment for PCOS. In present non-randomized, open label pilot study, we have studied safety and effectiveness of exclusive natural mineral solution with use of reserve wellness wrapping technique in PCOS patients. Methods: A total of 20 females (10 married and 10 unmarried) who had with PCOS were enrolled in present study. Natural Mineral powder used for study consist of mixture of Bentonite Clay, Magnesium Chloride, Magnesium Sulphate, Sodium Chloride and Zinc Oxide 2%. Patients were underwent standard study procedure. Changes in hormonal level (AMH, LH, FSH, Prolactin, TSH, Insulin resistance) measured on 3rd day of menstrual cycle pre-treatment and post treatment was evaluated to assess the efficacy of study treatment. Safety was evaluated throughout study procedure by observing adverse events. Compliance to study treatment was documented on individual case report form of the patient. Results: Study results revealed that majority of hormonal level significantly changed post treatment compared to pre-treatment. LH/FSH Ratio at pre-treatment was 2.76:1, which was reduced to 1.21:1 at posttreatment (p< 0.001). Study results shown that there was statistically significant improvement in Luteinizing Hormone (LH), Prolactin, AMH, Fasting Insulin, SGPT, post treatment from the preoperative values (P < 0.05). No adverse event was reported during conduct of present study. Conclusions: Present study procedure for PCOS treatment is found safe and efficacious without any incidence of adverse events.