Journal of Biomedical Sciences

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Potentially Inappropriate Medication Use among Older Adults using the 2019 American Geriatrics Society Beers Criteria

Bedilu Linger Endalifer*, Yenesew Wudu and Asmamaw Yenesew Tamer

Background: The number of elderly people expected to grow from 524 million in 2010 to 1.5 billion in 2050, predominantly in developing countries. Older people are prone to age-related disease comorbidity, and poly pharmacy, which made medication prescription often inappropriate and inaccurate. Therefor prescribing medication appropriately is concerning issues in older adults. This study was aimed to determine the prevalence of potentially inappropriate medication use and associated factors in an Ethiopian hospital.

Methods: A facility-based cross-sectional study design was employed for patients aged 65 and above years. American geriatrics society Beers 2019 evidence-based criteria were used to collect data and to identify Potential inappropriate medications. Descriptive statistics and binary logistic regression were used to describe and identify potential predictors of PIMs use. Statistical analyses were done by using the Statistical package for social science Software version 23 (SPSS ® 23).

Results: From 675 older patients visited during the study period, 236 patients were included in the study. The magnitude was 47% with 131 PIMs giving a mean ± SD of 1.2 ± 0.5 were identified during the study period. Most of the patients 95 ( 40.3%) had only one PIM and Glibenclamide was the most common inappropriately prescribed drugs. Patients with cardiovascular disorder (AOR=4.0, 95% CI; 2.0, 8.4) and endocrine disorder (AOR=2.6; 95% CI, 1.5, 4.6) had significant association with PIM use.

Conclusion: Prescribing of PIM is common among Ethiopian elderly patients. The patient's having cardiovascular disorders or endocrine disorders were more likely to have increased use of PIMs among older patients.

Published Date: 2021-12-23; Received Date: 2021-12-03