Objective: Describe the modalities for the management of Primary nasal lymphoma. Materials and methods: We report the case of a 63-year-old man who presented with Primary nasal lymphoma. Case report: This is a 63-year-old patient admitted to the emergency department. He was consulted for progressive nasal obstruction, first unilateral right then bilateral, complete on the right and partial on the left, with rhinorrhoea mucopurulent streaked with blood. On inspection, there is a swelling in the right nasal fossa protruding through the nostril opening and effacing the nasolabial fold, with the facing skin inflamed. A biopsy of the mass with pathological examination and immunohistochemical study (IHC) confirmed the diagnosis of plasma cell lymphoma. The remainder of the extension record was normal. The patient received 5 courses of adjuvant chemotherapy according to the CHOP protocol (adriamycin + vincristine + cyclophosphamide + prednisone), followed by locoregional external radiotherapy (sinuses and nasal cavities) at a dose of 48.6 Gy in 27 sessions. Conclusion: Nasosinus lymphomas represent a rare entity, characterized by initial symptomatology often rough, delaying the diagnosis. Radiology is non-specific, and the diagnosis remains histological. Chemotherapy adjuvant to radiotherapy gives good results.