Elahe Nasri, Hossein Mirhendi, Behrooz Ataei, Afsane Vaezi, Somayeh Sadeghi and Hamed Fakhim
The coronavirus disease 2019 (COVID-19) emerged in December 2019 and has rapidly spread worldwide. The overall mortality rate differs between regions, countries, and different patients risk factors. With many infections, immune compromised patients often present with signs and symptoms that are atypical. Herein we report a case of a SARS-CoV-19 infection in a patient with chronic lymphocytic leukemia (CLL) and describe the clinical course, diagnosis, and management of the case. The initial presenting clinical symptoms were dyspnea and cough, followed by sore throat and headache and progression to pneumonia. He was admitted once more with dry cough and fever, without dyspnea after 42 days and treated with 400 mg/kg body weight intravenous immunoglobulin (IVIG) single dose. This case highlights the importance of COVID-19 infection in immune compromised patients which would be considered in the presence of different presentation and screening procedures. In conclusion, the differential diagnosis of COVID-19 should be pursued when investigating in CLL patient with signs and symptoms of pneumonia.