We report a 40-year-old female diagnosed with histological grade III meningioma of OMS 2016 in the right side of the temporo-parietal region of skull vault. After a partial resection of the primary site, she rapidly developed unusual multiple metastasis in the pulmonary parenchyma. The patient received adjuvant radiotherapy on the residual volume with palliative decompressive intent due to the gross tumor volume. A review of the literature revealed well documented cases of benign meningiomas that metastasized in an interval of up to 10-12 years after primary tumor resection. This case illustrates that meningiomas Grade III WHO with progression disease of the primary tumor have the potential to develop hematogenous rapid metastases, emphasize the role of multimodal management and the role of genetic behavior to predict such evolution.
Published Date: 2022-01-31; Received Date: 2022-01-05