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Translational Biomedicine

  • ISSN: 2172-0479
  • Journal h-index: 12
  • Journal CiteScore: 8.06
  • Journal Impact Factor: 1.0
  • Average acceptance to publication time (5-7 days)
  • Average article processing time (30-45 days) Less than 5 volumes 30 days
    8 - 9 volumes 40 days
    10 and more volumes 45 days
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Abstract

Research in Translational Biotechnology.

Jose William*

The research projects are focused on the molecular mechanisms involved within the maintenance of the integrity of the mammalian genome which play a central role in carcinogenesis and in evolution. The main structures needed for the upkeep of functional and structural chromosome integrity are centromeres and telomeres. Mammalian centromeres are typically associated to highly repetitive DNA (satellite DNA); this pattern of organisation hampered an in depth molecular analysis of centromeric chromatin.