Journal of Neurology and Neuroscience

  • ISSN: 2171-6625
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Significance of Striational Antibodies in the Context of Neuropathy

Faisal Anwar and Mark Flemmer

A 88-year-old Caucasian male diagnosed with prostate cancer and treated 1 year ago with transurethral resection of the prostate presents with a 3-month history of progressive fatigue/ malaise, and ataxia with inability to ambulate. He was previously able to ambulate with assistance. On exam, he had a positive Romberg sign which has been present for years, as well as loss of proprioception and vibration sense in both lower extremities in addition to patellar areflexia and dysmetria. He was on many sedatives, which after holding during hospitalization, did not result in any improvement in his functional status. He was compliant with degarelix for prostate cancer treatment. A bone scan showed uptake in the anterior left 6th rib, anterior left iliac crest, and left ischium suspicious for metastatic disease.