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International Journal of Drug Development and Research

  • ISSN: 0975-9344
  • Journal h-index: 49
  • Journal CiteScore: 11.20
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Abstract

Syntheses of some novel 5-Substituted-Arylidene-3-Substituted- Benzyl-Thiazolidine-2, 4-Dione Analogues as Anti-Hyperglycemic Agents

Garg Ankush, Chawla Pooja, Saraf A Shubhini

A series of 5-substituted-arylidene-3-substitutedbenzyl- thiazolidine-2, 4-dione derivatives were synthesized through Knoevenagel condensation and studied for their glucose lowering capability against alloxan induced diabetic rats. Some of the compounds showed appreciable antidiabetic activity comparable to standard drug rosiglitazone.