Taraszkiewicz-Sulik Katarzyna, PekaÃƒâ€¦Ã‚â€ša Gabriela, Golebiewska Maria and Musial Wlodzimierz
Introduction: Inflammatory process plays a great role in pathogenesis and development of many of the systemic diseases, including Cardiovascular Disease and Incident Cardiovascular Events (CVEs). Interleukin-6 and C-reactive protein are recognized as an inflammatory markers.
The Aim of the Study: To assess the level of the inflammatory markers: hs-CRP and IL-6, related to the number of remaining teeth in post-myocardial infarction patients, treated with primary coronary angioplasty (pPCI). Materials and Methods: The research was based on 80 people, 32 women and 48 men aged 34-82. Within this sample of 80 people, 50 had previously suffered a heart attack while 30 were in good general health. The partially edentulous arches were classified with Galasinska- Landsbergerowa classification and the number of remaining teeth was assessed in both groups. The level of hs-CRP was measured with nephelometric method, IL-6 with immunoenzymatic method (ELISA). For statistical analysis the Statistica 10.0 software was used.
Results: In the post-myocardial infarction male group, the statistically significant negative correlation between IL-6 level and the mean remaining teeth in general, as well as in mandible was observed. However no correlation between the number of remaining teeth and CRP level, in postmyocardial patients, was noticed.
Conclusion: Increased level of hs-CRP and IL-6 in research confirms the hypothesis, that unsatisfactory oral hygiene status raises the risk of myocardial infarction. Hence, there is a necessity of creation and implementation of professional preventive-therapeutic-educational program dedicated directly to cardiac high risk group.