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The Management of Sentinel Lymph Node Biopsy in Breast Cancer

Victor Titirez, Roxana Elena MiricÄ?

Breast cancer is a public health issue due to its high incidence and mortality in advanced stages. As breast cancer is lymphophilic (the disease is spread mainly through the lymphatic system), axillary surgery remains essential in the treatment and staging of this condition. Sentinel lymph node biopsy has become the gold standard for axillary nodal staging, successfully replacing total axillary lymphadenectomy. This procedure has evolved significantly in the last 30 years and represents a topic of great relevance and interest. Certain issues related to the sentinel lymph node (identification techniques, indications and contraindications, the role of adjuvant therapy), will be highlighted in this paper.