Flyer

Journal of Biomedical Sciences

  • ISSN: 2254-609X
  • Journal h-index: 14
  • Journal CiteScore: 5.48
  • Average acceptance to publication time (5-7 days)
  • Average article processing time (30-45 days) Less than 5 volumes 30 days
    8 - 9 volumes 40 days
    10 and more volumes 45 days
Indexed In
  • Genamics JournalSeek
  • China National Knowledge Infrastructure (CNKI)
  • Directory of Research Journal Indexing (DRJI)
  • OCLC- WorldCat
  • Google Scholar
  • Secret Search Engine Labs
Share This Page

Abstract

The Study of the Content of N-Acetylneuraminic Acids in Membranes of Erythrocytes in Patients with Glaucoma

Hovsepyan L, Ghazaryan G and Hasmik Zanginyan

The aim of this work was to study the content of total and lipid-bound neuraminic (sialic) acid in erythrocyte membranes in patients with glaucoma. The results of our studies showed that glaucoma is accompanied by an increase in the total content of neuraminic acid obtained from glycoproteins and glycolipids. A study of the content of gangliosides made it possible to detect a decrease in all fractions of gangliosides, which is associated with the hydrolytic breakdown of gangliosides and with the increase of free neuraminic acid. The data obtained are interpreted in connection with the destruction of membranes, leading to a disruption of cellular functions.