Translational Biomedicine

  • ISSN: 2172-0479
  • Journal h-index: 18
  • Journal CiteScore: 5.91
  • Journal Impact Factor: 4.11
  • Average acceptance to publication time (5-7 days)
  • Average article processing time (30-45 days) Less than 5 volumes 30 days
    8 - 9 volumes 40 days
    10 and more volumes 45 days
Awards Nomination 20+ Million Readerbase
Indexed In
  • Open J Gate
  • Genamics JournalSeek
  • JournalTOCs
  • ResearchBible
  • The Global Impact Factor (GIF)
  • China National Knowledge Infrastructure (CNKI)
  • CiteFactor
  • Scimago
  • Electronic Journals Library
  • Directory of Research Journal Indexing (DRJI)
  • OCLC- WorldCat
  • Proquest Summons
  • Publons
  • MIAR
  • University Grants Commission
  • Geneva Foundation for Medical Education and Research
  • Google Scholar
  • Secret Search Engine Labs
  • ResearchGate
Share This Page


Topical application of human milk reduces umbilical cord separation time and bacterial colonization compared to ethanol in newborns

Ebtsam S Mahrous , Mirret M. Darwish , Soheir A. Dabash , Ibrahim Marie , Sayed F Abdelwahab

Background: Umbilical cord infections contribute to the increased morbidity and mortality in newborns of developing countries, where infants are exposed to unhygienic practices. The best umbilical cord treatment after birth is a controversial issue. There are limited data examining the effect of topical application of human milk on newborns’ cord separation and bacterial colonization, which is examined herein and compared to 70% ethanol.

Methods and Findings: One hundred neonates attending Minia University Hospital were enrolled in a quasi-experimental design (50 neonates in each group). Cord separation time was recorded. Microbiological examination including total viable bacterial count (TVC) and identification of the implicated bacterial species was performed at birth, day 3 and at cord separation time. The mean cord separation time in the human milk and alcohol groups were 4.3±1.4 (SD) and 8.2±2.2, respectively (p<0.001). There were significant differences between the two groups in the TVC (p<0.001). The isolated organisms included Staphylococcus epidermidis, Staphylococcus aureus,  Micrococci, Escherichia coli  and Klebsiella species, with higher rates of pathogenic species in the ethanol group.

Conclusion: Topical application of human milk reduces cord-separation time and pathogenic bacterial colonization and can be used as easy, cheap and non invasive methods for umbilical cord care in developing countries.