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International Journal of Drug Development and Research

  • ISSN: 0975-9344
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- (2010) Volume 2, Issue 1

ANTIHYPERLIPIDEMIC ACTIVITY OF MOMORDICA DIOICA ROXB

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Abstract

The inhibitory effect of the ethanolic extract of fruits of Momordica dioica Roxb. was tested in hyperlipidemic rats using two animal models induced using Triton WR-1339 as and by 30% corn oil. At the dose of 500 mg/kg p.o the ethanolic extract of fruits of Momordica dioica Roxb. reduced the total cholesterol, serum triglyceride, HDL-cholesterol, LDL-cholesterol and VLDL- cholesterol levels significantly as measures of its hypocholesterolemic or hypolipidemic effects. Thus, the ethanolic extract of fruits of Momordica dioica Roxb. was found to be active using these two hypolipidemic assays

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