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Perspective - (2022) Volume 14, Issue 2

Drugs Treating Other Disorders Could Have Psychiatric Adverse Effects

Wang Cheng*
 
The Departments of Medicine and Psychiatry, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America
 
*Correspondence: Wang Cheng, The Departments of Medicine and Psychiatry, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America, Email:

Received: 28-Jan-2022, Manuscript No. ipaom-21-12653; Editor assigned: 05-Feb-2022, Pre QC No. P-12653; Reviewed: 17-Feb-2022, QC No. Q-12653; Revised: 22-Feb-2022, Manuscript No. R-12653; Published: 28-Feb-2022

Perspective

Many medications used to treat nonpsychiatric illnesses can have neuropsychiatric side effects. Sedation, sleep disturbance, anxiety, sadness, mania, psychosis, cognitive disturbance, and delirium are just a few of the side effects that have been described. The reactions are usually dose-related, although they can also happen at therapeutic dosages or after a long period of drug usage. They're more common in elderly or unwell people, as well as those with a mental background, and they can be unpredictable or contradictory. Here are a few of the most prevalent psychiatric side effects of medications used to treat non-psychiatric diseases. Dopaminergic and anti-muscarinic drugs for Parkinson's disease; digitalis and -adrenoceptor antagonists for cardiovascular disorders; cannabinoid receptor antagonists for obesity; corticosteroids for endocrine disorders, asthma, and allergic conditions; and anti-infective drugs for bacterial, parasitic, and viral infections are just a few case studies.

Introduction

Many medications used to treat non psychiatric illnesses can have neuropsychiatric side effects. Sedation, sleep disturbance, anxiety, sadness, mania, psychosis, cognitive disturbance, and delirium are just a few of the side effects that have been described. The reactions are usually dose-related, although they can also happen at therapeutic dosages or after a long period of drug usage. They're more common in elderly or unwell people, as well as those with a mental background, and they can be unpredictable or contradictory. Here are a few of the most prevalent psychiatric side effects of medications used to treat non-psychiatric diseases. Dopaminergic and anti-muscarinic drugs for Parkinson's disease; digitalis and -adrenoceptor antagonists for cardiovascular disorders; cannabinoid receptor antagonists for obesity; corticosteroids for endocrine disorders, asthma, and allergic conditions; and anti-infective drugs for bacterial, parasitic, and viral infections are just a few case studies. Many medicines can produce psychiatric symptoms, although establishing a direct link is typically challenging. Psychiatric symptoms that arise as a result of pharmacological treatment could be attributable to the underlying illness, previously undiagnosed psychopathology, or psychosocial factors. Withdrawal symptoms from various medicines include anxiety, psychosis, delirium, agitation, and depression. Several internal medicine medications can have Psychiatric Side Effects (PSEs) that are similar to symptoms found in psychiatry. PSEs can happen as a result of withdrawal or intoxication, as well as at normal therapeutic levels. Corticosteroids, isotretinoin, levodopar mefloquine, interferon-a, and anabolic steroids, as well as numerous over-the-counter drugs, can all cause depressive, anxious, or psychotic symptoms. PSEs are notoriously difficult to detect and can be quite dangerous to patients.A wide range of drugs used to treat physical sickness have been linked to psychiatric Adverse Drug Reactions (ADRs). Some are modest (such as transitory sleep disruptions), while others are severe (such as psychosis) and require the suspected causative agents to be stopped. Some responses are predictable, while others are unpredictably unpredictable. Often, the mechanism by which they are communicated is unknown. Because many major mental ADRs are quite infrequent and may only be found by post marketing surveillance in the general population, it is critical that they be reported via the UK's Yellow Card reporting scheme. Patients have described mental ADR symptoms as exceedingly unpleasant and even terrifying, and may be hesitant to discuss them with prescribers.This study shows that druginduced PSEs can occur with a variety of internal medicine drugs, and that these adverse effects are often neglected. For patients and their families, a PSE can be a difficult and distressing experience. A person without known psychiatric antecedents who develops a drug-induced psychosis, for example, may experience consequences such as the dread of losing their mind or institutionalisation in a mental ward. A PSE may produce posttraumatic stress disorder in some situations, either because of the severity of the PSE or because of a poor explanation of the side effect to the patient [1-5]. Another point to consider is the significance of correctly diagnosing a PSE. This is significant for a number of reasons. The most important is likely to assist patients in making appropriate attributions and inferences about their psychological alterations. Indeed, knowing that a PSE is a side effect has a different meaning for someone who is experiencing it than worrying if they are mentally ill. Detecting a PSE prevents it from being misdiagnosed as a psychiatric symptom; because spontaneous psychiatric diseases frequently necessitate long-term treatment, a correct diagnosis of a PSE can save the patient the embarrassment, distress, and other costs of unjustified long-term psychiatric treatment. Finally, the precise diagnosis of a PSE allows the prescriber to report any potential adverse effects to the pharmacovigilance organisation.

Conflicts of Interest

The authors declare no competing interests.

All authors declare that the material has not been published elsewhere, or has not been submitted to another publisher.

Data Availability

Authors declare that all related data are available concerning researchers by the corresponding author's email.

References

  1. Cotlar AM (2002) Historical landmarks in operations on the colon—Surgeons courageous. Current Surgery. 59: 91-95.
  2. [Google Scholar], [Crossref]

  3. Wright HK, O'Brien JJ, Tilson MD (1971) Water absorption in experimental closed segment obstruction of the ileum in man. Am J Surg 121: 96-99.
  4. [Google Scholar], [Crossref]

  5. Tiwari SJ, Mulmule R, Bijwe VN (2017) A clinical study of acute intestinal obstruction in adults-based on etiology, severity indicators and surgical outcome. Int J Res Med Sci 5: 3688-3696.
  6. [Google Scholar], [Crossref], [Indexed at]

  7. Souvik A, Hossein MZ, Amitabha D, Nilanjan M, Udipta R (2010) Etiology and outcome of acute intestinal obstruction:  A review of 367 patients in Eastern India. Saudi J Gastroenterol 16: 285.
  8. [Google Scholar], [Crossref]

  9. Tabrez MO, Chandak SR (2016) To study the clinical profile and management of acute small bowel obstruction at Acharya Vinobha Bhave Rural Hospital, Sawangi (Meghe), Wardha. Int J Sci Res 5: 1636-1639.
  10. [Google Scholar], [Crossref]

Citation: Cheng W (2022) Drugs Treating Other Disorders Could Have Psychiatric Adverse Effects. Arch Med Vol. 14 No. 2:9. DOI: 10.36648/1989-5216.21.14.72