Department of Chemistry, University of Podlasie, 3-Maja 54, Siedlce, Poland, PL- 08-110, Poland
Commentary
A Note on Purine Analogues with Electronic Absorption in the Visible Region.
Author(s): Andrzej Rykowski
The absorption spectrum of some 5-substituted derivatives was found to extend to the visible region. These compounds were found to inhibit some enzymes of purine metabolism, like xanthine oxidase or bacterial purine-nucleoside phosphorylase with Ki values in the 10-3 –10-5 M range.
Keywords
Thiazine; Purine analogues; Enzyme inhibitors; Spectroscopic probes. .. View More»