Department of Pathology and Immunology and Molecular and Cellular Biology Program University, School of Medicine 660 South Euclid Avenue, St. Louis, Missouri 63110, USA
Perspective
A Short Note on Systematic Approach in Biological Research and Drug Discovery
Author(s): Steven Zheng X.F
Traditional biological research and natural product drug discovery to a systematic operation in genomics and target-specific drug design and selection. Small, cell- permeable and target-specific chemical ligands are particularly useful in systematic genomic approaches to study biological questions. On the other hand, genomic sequence information, comparative and structural genomics, when combined with the cutting edge technologies in synthetic chemistry and ligand screening/ identification, provide a powerful way to produce target-specific and/or function- specific chemical ligands and drugs. Chemical genomics or chemo genomics is a new term that describes the development of target-specific chemical ligands and the use of such chemical ligands to globally study gene and protein functions. We anticipate that chemical genomics plays a critical role in the genomic age of biological resea.. View More»
Spanish 
Chinese 
Russian 
German 
French 
Japanese 
Portuguese 
Hindi 