Archives of Clinical Microbiology

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Biological Characters of Vancomycin Resistant Staphylococcus aureus Isolates from a University Hospital in Egypt

Fatma Ibrahim S, El-Said El-Banna T, Abd El-Aziz AA and El-Ekhnawy E

Background: Vancomycin resistance in Staphylococcus aureus in many cases appears to be associated with some biological changes.

Methods and Findings: In this study 88 vancomycin resistant Staphylococcus aureus (VRSA) were isolated from Tanta. Antibiotic susceptibility test was performed. Some of its biological characters were studied including autolytic activity, coagulase production, surface hydrophobicity and biofilm formation.

Conclusion: As observed, vancomycin MICs of the selected VRSA isolates were directly proportional to their hydrophobicity index and biofilm production. On the other hand, MICs were inversely proportional to coagulase activity (the higher the dye diffusion, the lower the coagulase activity).