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International Journal of Drug Development and Research

  • ISSN: 0975-9344
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Abstract

Comparative Anthelmintic Activity of Aqueous and Ethanolic Leaf Extracts Of Clitoria Ternatea

Manoj Salhan, Bimlesh Kumar, Prashant Tiwari, Pardeep Sharma ,Harleen Kaur Sandhar, Mayur Gautam

The present study aimed at the in-vitro comparative study of anthelmintic activity of aqueous and ethanolic extracts of leaves of Clitoria ternatea using Eisenia foetida at three different concentrations (100, 50, 25 mg/ml) respectively. The study involved the determination of time of paralysis (P) and time of death (D) of the worms. At the concentration of 100 mg/ml both the ethanolic and the aqueous extracts showed very significant activities as compared to the standard drug levamisole (0.55 mg/ml). In case of aqueous extract the time of paralysis and death time was observed as 18 ± 1.57 and 53.33 ± 0.33 and in case of ethanolic extracts 12.33 ± 0.80 and 32.33 ± 0.71 respectively. In conclusion, the use of leaves of Clitoria ternatea as an anthelmintic have been confirmed and further studies are suggested to isolate the active principles responsible for the activity