Translational Biomedicine

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Effect of Pinus koraiensis seed oil on satiety hormones CCK and GLP-1 and appetite suppression

Zamola Frantisek , Krewel Meuselbach

Obesity is a serious public health challenge. In recent years various strategies for treatment of obesity are researched. Because oflimitations of drugs currently available, new preparations for treatment are searched (especially safe natural products). PinnoThinâ„¢,Korean pine nut oil with high content of pinolenic acid, was subjected to two studies, which evaluated its influence on satiety hormonescholecystokinin and glucagon like peptide 1. The results of the studies confirmed, that pine nut oil is capable of increase ofsatiety hormones release and therefore it suppresses appetite. It does not have any effect on hunger inducing factor ghrelin. Thestudy of toxicity showed that pine nut oil is not toxic and so it is safe for obesity treatment.