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Archives of Clinical Microbiology

  • ISSN: 1989-8436
  • Journal h-index: 22
  • Journal CiteScore: 7.55
  • Journal Impact Factor: 6.38
  • Average acceptance to publication time (5-7 days)
  • Average article processing time (30-45 days) Less than 5 volumes 30 days
    8 - 9 volumes 40 days
    10 and more volumes 45 days
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Abstract

Interaction of Helicobacter Pylori with Other Microbiota Species in the Development of Gastric Cancer

Xiaolin Liu, Weiwei Nie, Jing Liang and Yan Li

Gastric adenocarcinoma is the second-leading cause of cancer-related death in the world. Helicobacter pylori is a Gram-negative bacterial species that selectively colonizes gastric epithelium. The resulting chronic infection is the most significant risk factor for gastric adenocarcinoma identified so far. In the host, H. pylori interacts with microorganisms, which is likely involved in the development of gastric cancer. To identify H. pylori-associated bacteria and explore the contributions of these inter-bacterial events in the process of gastric cancer, we examined the interactions of H. pylori with other microbes in the microbiota community that are implicated in the development and progression of gastric cancer. A better understanding of the complex interactions between H. pylori and altered microbiota is critical to develop personalized therapies and approaches.