Annals of Clinical and Laboratory Research

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Massive Autosomal Dominant Polycystic Kidneys: Case Report of 18 kg Polycystic Kidneys

Nick Youssefi, Brian Remillard and Dartmouth-Hitchcock

Autosomal dominant polycystic kidney disease (ADPKD) is an inherited, progressive, systemic disorder with renal and extra renal involvement. The incidence is 1 in 500 to 1000, with 50% of cases progressing to end-stage renal disease by the age of 60. Renal manifestations include multiple cysts, pain, hypertension, hemorrhage, infection, and renal failure. Extra renal involvement includes liver cysts, intracranial aneurysms, mitral valve prolapse, and colonic diverticulosis [1]. We report a case of massive polycystic kidney disease requiring bilateral nephrectomy and hemodialysis.