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Maternal Diet and Epigenetic Modifications at the Start of Life: Repercussions on the Development of Obesity

Matheus Santos de Sousa Fernandes, Camila Tenório Calazans, Gabriela Carvalho Jurema Santos

Objectives: Thus, the objective of the study was to evaluate the repercussions of the maternal diet and epigenetic changes in early life and its repercussions on the development of obesity.

Methods: For this, a narrative review of a descriptive character was developed using the following descriptors: “Maternal diet”, “epigenetics” and “obesity”. The articles published between the years 2015 to 2020 were selected from the databases: Scientific Electronic Library Online (Scielo), National Library of Medicine (PubMed) and Virtual Health Library of the Ministry of Health (VHL).

Results: It was observed that the intake of maternal high-fat diets promotes the appearance of epigenetic changes that favor the appearance of diseases, such as diabetes mellitus, in addition to increasing food intake, and consequently increasing body weight.

Conclusions: Thus, the importance of healthy eating is observed during critical periods of development to prevent the onset of cardiometabolic diseases.