Hassan A. Saad*, Azza Baz, Mohamed Riad, Mohamed E Eraky, Mohamed I Farid, Huda EM Said, Eid Rizk Elgammal, Mervat Harira and Ahmed El-Sayed Yousef
The use of minimally invasive techniques has not attained the same widespread acceptance for the treatment of more advanced tumors, principally because of existing concerns about its feasibility Laparoscopy is rarely used to treat stomach malignancy. We compared the outcomes of laparoscopic gastrectomy with those of open surgery, and long term complication results evaluated. There is still a debate regarding whether one of these options is superior. We need to compare the primary and secondary outcomes of laparoscopic versus open gastrectomy in patients with locally advanced gastric cancer, therefore, complete acceptance as a legitimate therapy is hampered by the lack of thorough investigation of long-term oncological consequences, including recurrence and fatality.
Methods: We retrospectively evaluated patients who underwent laparoscopic ves open gastrectomy between February 2014 and November 2023. After collecting the database from the board sheet of our Zagzig University Hospital (throughout eight years), the patients were divided into two groups: Open surgery and laparoscopic surgery. Logistic regression was used to compare the 30-day full complications, mortality and long-term outcomes like recurrence rates and survival, which are crucial to comparing laparoscopic and open surgeries for advanced gastric cancer in both groups.
Results: The Risk Ratio (RR) and 95% Confidence Interval (CI) were calculated. For consistent results, the Mean Difference (MD) or Standardized Mean Difference (SMD) and 95% Confidence Interval (CI) were calculated. The meta-analysis was conducted using Review Manager 5.3 and STATA software. A total of 8,232 gastric cancer patients were divided into two groups based on the type of surgery they underwent: Open gastrectomy (n=7,450; 90.5%) and laparoscopic surgery (n=782; 9.5%). Preoperative measurement of risk variables was important (CI=0.45-0.82, p=0.001, Odds Ratio (OR) 0.61, 95% confidence interval). We found no significant differences in mortality between groups when the preoperative risk variable was measured (OR=0.74; 95% CI=0.32-1.72; p=0.481).
Published Date: 2026-02-17; Received Date: 2024-12-03
