Flyer

Health Science Journal

  • ISSN: 1791-809X
  • Journal h-index: 61
  • Journal CiteScore: 17.30
  • Journal Impact Factor: 18.23
  • Average acceptance to publication time (5-7 days)
  • Average article processing time (30-45 days) Less than 5 volumes 30 days
    8 - 9 volumes 40 days
    10 and more volumes 45 days
Awards Nomination 20+ Million Readerbase
Indexed In
  • Genamics JournalSeek
  • China National Knowledge Infrastructure (CNKI)
  • CiteFactor
  • CINAHL Complete
  • Scimago
  • Electronic Journals Library
  • Directory of Research Journal Indexing (DRJI)
  • EMCare
  • OCLC- WorldCat
  • MIAR
  • University Grants Commission
  • Geneva Foundation for Medical Education and Research
  • Euro Pub
  • Google Scholar
  • SHERPA ROMEO
  • Secret Search Engine Labs
Share This Page

Abstract

Sero-prevalence of IgG and IgA Antisperm Antibodies in Men with Infertility Attending Two Major Hospitals in Zaria, Nigeria

Oduma Audu, Bolanle Olufunke Priscilla Musa, Mukhtar Abdulmajid Adeiza, Ahmad Muhammed, Abdurrahman El-fulaty Ahmad, Bawa Ega, Suraju Ahmad Opaluwa and Bukhari Isah Shuaib

Background: Antisperm antibodies (ASA) have been implicated in some male with infertility especially those in which a definite cause could not be found. Also, some studies have attributed a causal relationship to the presence of antisperm antibodies and male infertility.

Objective: This study investigated the prevalence of serum antisperm antibodies in men with infertility seen in two Hospitals in Zaria, Nigeria

Materials and Methods: A total of 91 infertile men and 45 fertile men (as controls) were enrolled and follow up for 5 months. Blood samples and semen were collected, processed and analysed for serum IgA and IgG ASA using ELISA kits.

Results: The study revealed the sero-prevalence of antisperm antibodies among infertile men in Zaria to be 57.1%, which varied significantly with that of the fertile male (11.1%). The prevalence of IgA and IgG antisperm antibodies were significantly higher in infertile male compared to fertile male (27.5% vs 4.4% for IgA ASA; 53.8% vs 8.9% for IgG ASA).

Conclusion: The study demonstrated that IgA and IgG ASA are associated with male infertility in Zaria and as such screening for serum antisperm antibodies in the evaluation of men infertility is recommended in our environment.