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Síndrome de Hiperuricemia: Una Perspectiva Fisiopatológica Integrada

Víctor Adolfo Ríos-Barrera, César Francisco Pacheco-Tena, Alfredo Nevárez-Rascón and Martina Nevárez-Rascón

Hyperuricemia syndrome is relatively common in humans, affecting nearly a quarter of the population, with male predominance 3 to 4 times higher comparing with premenopausal women. Most patients with hyperuricemia (>90%) only show this finding without any evidence of symptomatology; however, the rest do have some clinical picture, being the most common Gout. Uric acid metabolism is complex, which causes its involvement in other conditions either directly or indirectly, either as a cause or consequently thereof. In this work we made a conceptual integration between the etiological, pathophysiological and clinical bases of this syndrome.