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Archives in Cancer Research

  • ISSN: 2254-6081
  • Journal h-index: 12
  • Journal CiteScore: 2.71
  • Journal Impact Factor: 2.30
  • Average acceptance to publication time (5-7 days)
  • Average article processing time (30-45 days) Less than 5 volumes 30 days
    8 - 9 volumes 40 days
    10 and more volumes 45 days
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Abstract

TH588 Potently Kills Melanoma Cells Grown in 3-Dimensional Culture Through Apoptosis Induced by ROS

Jia Yu Wang, Chen Chen Jiang, Xu Guang Yan, Lei Jin and Xu Dong Zhang

MutT homolog 1 sanitizes oxidized dNTP pools through converting 8-oxo-deoxy-guanine (8-oxo-dGTP) and 2-OHdeoxy- adenosine (2-OH-dATP) into the corresponding monophosphates, thus protecting cells from DNA damage caused by reactive oxygen species (ROS).