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Abstract

The Effect of Combined Exercise Versus Aerobic Exercise on Cognition and Mood among Hypertensive Older Adults: Randomized Clinical Trial

Wellington Santos*, Amanda Sardeli, Daisa Fabiele, Victor Gadelha, Arthur Fernandes Gaspari, Claudia Cavaglieri, Laura Middleton and Mara Patricia Chacon-Mikahil

Comorbidities such as hypertension is a risky factor to impair cognitive function in elderly. Both strength and aerobics (CT, combined exercise) or aerobics (AT) has potential benefits for healthy as well as hypertensive elderly. Our goal was to evaluate the effects of CT and AT on cognition and mood. 52 hypertensive older adults were randomized to 16 weeks of CT (n=26) or group control (GC) (n=26), after this period subjects in the CONTROL began AT (AT) for 16 weeks. Delta between post and pre were calculated and normality was tested. One-way ANOVA to compared groups (CT, AT and CONTROL) follow by post-hoc of by Hechberg and Kruskal-Wallis test followed by Mann-Whitney, for CT and GC or Wilcoxon for GC and AT, depending upon parametric assumption. Improvements in aerobics fitness for both CT and AT (H (2) = 13.89 p<0.001 and p<0.001), working memory (H (2) = 10.07, p=0.02 and p=0.007), speed processing (H (2) = 10.51, p=0.004 and p=0.019), and overall executive function (F (2, 42) = 4.862, p=0.05 and p=0.01) when compared to CONTROL. Improvement in depressive symptoms to CT (H (2) = 18.08, p<0.001) compared to CONTROL only and tendencies to improve short-term memory (F (2, 47) = 3.26, p=0.06) Both CT and AT improve cognitive functions (working memory, overall executive function, speed processing), only CT were able to modified depressive symptoms and shortterm memory. Additional benefits for CT would be attached to social interaction, improvement in blood flow or IGF-I release.

Published Date: 2022-01-27; Received Date: 2021-12-29