Molecular Enzymology and Drug Targets

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Ankit Mishra

Department of Psychology, University of Connecticut, United States

  • Mini Review   
    Delivery of Anti-Hiv Drugs of Targeting Strategies
    Author(s): Ankit Mishra*

    Infection with the human immunodeficiency virus continues to be a leading cause of death worldwide. The current antiretroviral therapy has a number of drawbacks, including toxicity, drug-drug interactions, the development of drug resistance, the need for long-term drug therapy, poor bioavailability, and lack of access to tissues and reservoirs, even though it has significantly decreased AIDS-related morbidity and mortality. Recent anti-HIV therapeutic research has concentrated on developing drug delivery methods that are selectively targeted to host cells that are HIV-infected or at risk of becoming HIV-positive in order to get around these issues. In this context, a number of surface molecules with both viral and host cell cellular origins have been identified in recent years, which might allow for the targeted administration of drugs to HIV-infected individuals. In this review, we g.. View More»

    DOI: 2572-5475-09.01-125

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